Valtrex 1000mg tablets

DESCRIPTION

Valtrex 1000mg includes an active composition like valacyclovir which is pharmacologically classify as nucleoside analogue of viral DNA polymerase prohibitor.

Valtrex 1000mg tablets which belongs to synthetically classified as nucleoside analogue. Valtrex 1000mg is usually present as prodrug which gets changed into an active molecule known as acyclovir.

INDICATION

The major indication of valacyclovir is used in the condition like;
Herpes simplex & Valtrex 1000mg herpes zoster
In adults
Valtrex 1000mg tablets is mostly indicated for the treatment of cold sores by Herpes Labialis. Valtrex 1000mg have capability to started after the advancement of clinical signs of cold sore has not been evaluated. Valtrex 1000mg is likewise determined in the condition like starting scene of genital herpes in immune capable grown -ups. Valtrex 1000mg tablets is also indicated in the treatment of relapsed episodes of genital herpes in immuno competent episodes. Valtrex 1000mg is exhibit for cutting edge suppressive therapy of repetitive scenes of genital herpes in immuno skillful and HIV-1 contaminated grown-ups. is also used for the contraction of transmission of genital herpes in immuno competent adults. Valtrex 1000mg tablets is indicated in the treatment of herpes zoster in immuno competent adults.
In pediatrics
In pediatric patients, Valtrex 1000mg tablets is includes in the therapy of cold sores with the age of greater or equal to 12 years. Valtrex 1000mg is also indicated for the therapy of chicken pox in immuno competent pediatric patients with age of 2 to less than 18 years.

Valtrex 1000mg tablets

PHARMACOLOGY

Valtrex 1000mg which represented as a prodrug that will go through phosphorylation by using viral thymidine kinase enzyme for changing of acyclovir triphosphate, an active metabolite. This active molecule is included in the prevention of herpes viral DNA Valtrex 1000mg tablets replication by competitive inhibition of viral DNA polymerase. After injected of this metabolite into the virus &causes terminate of the developing viral DNA chain. Valtrex 1000mg contains; TheDNA synthesis blocked Destabilizing the strand Prevention of new viral growth.

PHARMACOKINETICS

ABSORPTION

Valtrex 1000mg tablets After oral intake of Valtrex, valacyclovir is fast absorbed from the gastrointestinal tract Valtrex 1000mg and bioavailability by 54.5% plus or minus 9.1%.

DISTRIBUTION

Valtrex 1000mg After absorption occurs, the human serum protein binding capacity is 13 to 18%.

METABOLISM

Valtrex 1000mg is rapidly absorbed and approximately 99% of drug get changes into an active form like acyclovir & L-valine by sustaining first pass Valtrex 1000mg tablets metabolism & hepatic metabolism by enzymatic hydrolysis.

ELIMINATION

About 89% of radioactivity gets excreted via urine. The medianvalacyclovir Valtrex 1000mg half-life period occurs in 2.5 to 3.3 hours.

SIDE EFFECTS

THE MAJOR ADVERSE EFFECTS OF VALTREX ARE
Thrombotic thrombocytopenia purpura/hemolytic uremic syndrome, Acute renal failure, Central Valtrex 1000mg tablets nervous effects

THE COMMON SIDE EFFECTS

Valtrex 1000mg Low RBC Increased AST Neutropenia Respiratory tract infection Decreased Valtrex 1000mg tablets platelet counts Nasopharyngitis Headache Dizziness Nausea Abdominal pain

POST MARKETING EFFECTS

Valtrex 1000mg bVisual abnormalities Liver enzyme abnormality Hepatitis Renal failure Aplastic anemia Valtrex 1000mg tablets Erythema multiforme Alopecia Facial
edema High blood pressure Tachycardia Anaphylactic reactions CNS disorders

DRUG INTERACTIONS OF VALTREX

Valtrex 1000mg No drug- drug interactions occurs in the valacyclovir treatment.

CONTRAINDICATIONS OF VALTREX
Valtrex 1000mg is highly contraindicated in patients with hypersensitivity reactions due to patients are Valtrex 1000mg tablets contraindicated to the ingredients of Valtrex.

PREGNANCY & LACTATION

The pregnancy category of Valtrex 1000mg is B It should be used with caution. Caution should be taken while administering Valtrex 1000mg tablets to nursing woman.

MISSED DOSE

Valtrex 1000mg dose condition should be avoided by maintain the regular dosing schedule. Do not skip the dose.
If missed dose condition, Valtrex 1000mg tablets patient should be get discuss from the medical practitioner & follow the instructions. Avoid self-medication.

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