valtrex 500mg tablets

Valtrex 500mg



DESCRIPTION

Valtrex 500mg includes an active composition like valacyclovir which is pharmacologically classify as nucleoside analogue of viral DNA polymerase prohibitor.

Valtrex 500mg which belongs to synthetically classified as nucleoside analogue. Valtrex 500mg tablets is usually present as prodrug which gets changed into an active molecule known as acyclovir.

INDICATION

The major indication of Valtrex 500mg is used in the condition like;
Herpes simplex & herpes zoster
In adults
Valtrex 500mg is mostly indicated for the treatment of cold sores by Herpes Labialis. Valtrex 500mg tablets have capability to started after the advancement of clinical signs of cold sore has not been evaluated. Valtrex 500mg tablets is likewise determined in the condition like starting scene of genital herpes in immune capable grown -ups. Valtrex 500mg is also indicated in the treatment of relapsed episodes of genital herpes in immuno competent episodes. Valtrex 500mg tablets is exhibit for cutting edge suppressive therapy of repetitive scenes of genital herpes in immuno skillful and HIV-1 contaminated grown-ups. Valtrex 500mg is also used for the contraction of transmission of genital herpes in immuno competent adults. Valtrex 500mg is indicated in the treatment of herpes zoster in immuno competent adults.
In pediatrics
In pediatric patients, Valtrex 500mg tablets is includes in the therapy of cold sores with the age of greater or equal to 12 years. Valtrex 500mg is also indicated for the therapy of chicken pox in immuno competent pediatric patients with age of 2 to less than 18 years.

Valtrex 500mg

PHARMACOLOGY

Valtrex 500mg which represented as a prodrug that will go through Valtrex 500mg tablets phosphorylation by using viral thymidine kinase enzyme for changing of acyclovir triphosphate, an active metabolite. This active molecule is included in the prevention of herpes viral DNA replication by competitive inhibition of viral DNA polymerase. Valtrex 500mg tablets After injected of this metabolite into the virus &causes terminate of the developing viral DNA chain. Valacyclovir contains; Valtrex 500mg TheDNA synthesis blocked Destabilizing the strand Prevention of new viral growth.

PHARMACOKINETICS

ABSORPTION

After oral intake of Valtrex 500mg , valacyclovir is fast absorbed from the gastrointestinal tract and bioavailability by 54.5% plus or minus 9.1%.

DISTRIBUTION

After absorption occurs, the Valtrex 500mg human serum protein binding capacity is 13 to 18%.

METABOLISM

Valacyclovir is rapidly Valtrex 500mg tablets absorbed and approximately 99% of drug get changes into an active form like acyclovir & L-valine by sustaining first pass metabolism & hepatic Valtrex 500mg metabolism by enzymatic hydrolysis.

ELIMINATION

Valtrex 500mg About 89% of radioactivity gets excreted via urine. The medianvalacyclovir half-life Valtrex 500mg tablets period occurs in 2.5 to 3.3 hours.

SIDE EFFECTS

THE MAJOR ADVERSE EFFECTS OF VALTREX ARE

Thrombotic thrombocytopenia Valtrex 500mg tablets purpura/hemolytic uremic syndrome, Acute Valtrex 500mg renal failure, Central nervous effects

THE COMMON SIDE EFFECTS

Valtrex 500mg Low RBC Increased AST Neutropenia Respiratory tract infection Decreased platelet counts Nasopharyngitis Valtrex 500mg tablets Headache Dizziness Nausea Abdominal pain

POST MARKETING EFFECTS
Valtrex 500mg Visual abnormalities Liver enzyme abnormality Hepatitis Renal failure Aplastic Valtrex 500mg tablets anemia Erythema multiforme Alopecia Facial
edema High blood pressure Tachycardia Anaphylactic reactions CNS disorders

DRUG INTERACTIONS OF VALTREX

No drug- Valtrex 500mg drug interactions occurs in the valacyclovir treatment.

CONTRAINDICATIONS OF VALTREX

Valtrex 500mg is highly contraindicated in patients with hypersensitivity reactions due to patients are Valtrex 500mg tablets contraindicated to the ingredients of Valtrex.

PREGNANCY & LACTATION

The pregnancy category of Valtrex 500mg is B It should be used with caution. Caution should be taken while Valtrex 500mg tablets administering Valtrex 500mg to nursing woman.

MISSED DOSE

Valtrex 500mg Missed dose condition should be avoided by maintain the regular dosing schedule. Do not skip the dose.
If missed dose condition, patient should be get discuss from the medical Valtrex 500mg tablets practitioner & follow the instructions. Avoid self-medication.

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